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Description
Ramos-Blue™ cells derive from a human Burkitt's lymphoma which is negative for Epstein Barr virus. They have the characteristics of B lymphocytes and are routinely used as a model of B lymphocytes and for apoptosis studies. Ramos-Blue™ cells stably express an NF-κB/AP-1-inducible SEAP (secreted embryonic alkaline phosphate) reporter construct.
Ramos-Blue™ cells express several pattern recognition receptors, including TLR3, TLR7 and TLR9. The Ramos-Blue™ cell line was isolated for its ability to respond to CpG ODNs (TLR9 ligands).
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Ramos-Blue cells